All Compounding

Compounded Therapy

Low-Dose Naltrexone (LDN)

Low-dose naltrexone is a prescription therapy prepared in strengths that are not commercially manufactured. America First Pharmacies compounds LDN in Irving, Texas, to the exact strength your prescriber writes.

Prescription required

What's Included:

  • What Low-Dose Naltrexone Is
  • Why LDN Comes From a Compounding Pharmacy
  • Safety and What to Discuss With Your Prescriber
Low-Dose Naltrexone (LDN)

Naltrexone is a long-established prescription medication. At low doses, typically 0.5 to 4.5 mg, it is not available as a manufactured product, so it must be prepared by a compounding pharmacy. When your prescriber determines a commercially available product is not right for you, we prepare LDN to their exact specifications.

Every LDN prescription we fill is made for one person, you. Our pharmacists compound each strength to order, which matters with LDN because prescribers often start low and adjust gradually. If your prescriber changes your dose, we prepare the new strength exactly as written.

You will also work with a pharmacist who knows your name. We are an independent pharmacy in Irving, and we take time to walk through how to take your LDN and what questions to bring back to your prescriber along the way.

  • Capsules from 0.5 mg to 4.5 mg, made to the strength your prescriber writes
  • Sublingual preparations that dissolve under the tongue
  • Topical cream for prescriptions written for skin application
  • Step-up strength schedules when your prescriber starts low and adjusts
  • Formulations that avoid certain dyes or fillers when your prescriber requests it
  • Pharmacist time to walk through how to take your LDN
  • Coordination with your prescriber on strength changes
  • Refill reminders and local delivery options

What Low-Dose Naltrexone Is

Naltrexone has been used in medicine for decades at higher strengths. In recent years, some prescribers have written it at much lower strengths for certain chronic conditions. This use is considered off-label, and research is ongoing. Whether LDN is appropriate for you is a decision only you and your prescriber can make.

Why LDN Comes From a Compounding Pharmacy

Low-dose strengths of naltrexone are not commercially manufactured. When your prescriber determines that a commercially available product is not right for you, a compounding pharmacy prepares the prescribed strength to order. At America First Pharmacies, our pharmacists prepare each LDN prescription in-house in Irving, in the strength and form your prescriber specifies. A valid prescription is required before we can prepare anything.

Safety and What to Discuss With Your Prescriber

Naltrexone blocks opioid receptors. If you take opioid pain medications, including some cough and anti-diarrheal medicines, tell your prescriber before starting LDN, because the combination can cause serious problems including withdrawal symptoms and loss of pain control. Also discuss any liver conditions, all medications and supplements you take, and whether you are pregnant or nursing. Some people report vivid dreams or sleep changes when starting LDN, and your prescriber may adjust your dose or timing. Bring questions to your prescriber, or call our pharmacists and we will talk through your prescription with you.

Available Dosage Forms

Capsules

Compounded in strengths from 0.5 mg to 4.5 mg, matched exactly to your prescription.

Sublingual

Dissolves under the tongue, an option your prescriber may choose if swallowing capsules is difficult.

Topical Cream

Applied to the skin, prepared when your prescriber writes for a topical route.

Prescribers may consider this for

  • Chronic inflammation
  • Autoimmune symptoms
  • Fibromyalgia
  • Chronic pain

Common Questions

Visit or Call

7801 Mesquite Bend Dr. #108, Irving, TX 75063

Pharmacy hours

Mon–Fri: 9:30 a.m.–3:30 p.m.

Sat–Sun: Closed

Important Information

Compounded medications are prepared by a licensed pharmacist for an individual patient pursuant to a valid prescription from a licensed prescriber. Compounded medications are not FDA-approved. The FDA does not review compounded medications for safety, effectiveness, or quality before they are dispensed.

Prescription required. Compounded medications are dispensed only with a valid, patient-specific prescription. Ask your physician or prescriber whether a compounded medication is appropriate for you.

Information on this page is for educational purposes and is not medical advice. Individual results vary, and no outcome is guaranteed. Always consult your healthcare provider about your treatment options.

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