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Compounded Hormone Therapy
Hormone Pellet Therapy
America First Pharmacies compounds testosterone and estradiol pellets when your prescriber determines a commercially available product is not right for you. A prescription is required, and a trained clinician places the pellet in their office, not at the pharmacy.
Prescription required
What's Included:
- How We Compound Your Pellets
- What to Expect After Insertion
- Safety and What to Discuss With Your Prescriber
Hormone pellets are small, slow-release implants, each about the size of a grain of rice. They are compounded with testosterone or estradiol and placed under the skin, where they release medication gradually over several months. America First Pharmacies prepares each pellet from a prescription written specifically for you, at the strength your prescriber orders.
The pharmacy does not place pellets. Insertion is done by a trained clinician in their own office. It is a short visit. The clinician numbs a small area, usually on the hip or upper buttock, makes a small opening in the skin, places the pellet, and closes the site. Most patients go home the same day with a few days of simple aftercare instructions.
Pellet therapy is one option among several, not a default. Prescribers may consider it for patients who cannot use a commercially available hormone product, for example when a needed strength is not manufactured or when daily creams, patches, or injections have not been workable. Your prescriber weighs your labs, symptoms, and health history before deciding whether hormone therapy fits at all, and in which form.
- Compounded testosterone pellets
- Compounded estradiol pellets
- Strengths prepared to your prescriber's exact order
- Coordination with your prescriber's office on insertion timing
- Pharmacist counseling before your first insertion
- Help transferring an existing pellet prescription
- Refill reminders timed to your insertion schedule
How We Compound Your Pellets
America First Pharmacies prepares testosterone and estradiol pellets in our Irving compounding lab, made to order from a prescription written for you. Each pellet is compounded to the strength your prescriber specifies. We coordinate directly with your prescriber's office on the prescription and the insertion timing, and our pharmacists are available to answer questions before your first placement.
What to Expect After Insertion
The pellet dissolves on its own over several months and does not need to be removed at the end of a cycle. Your prescriber typically schedules follow-up labs to check hormone levels and decide whether and when another pellet makes sense. Keep the insertion site clean, follow your clinician's aftercare instructions, and contact their office if you notice redness, swelling, or a pellet working toward the surface of the skin.
Safety and What to Discuss With Your Prescriber
Pellet therapy carries specific risks that are worth understanding before you decide. Once a pellet is placed, the dose cannot be adjusted, and the pellet cannot easily be removed. If side effects occur, they may continue until the pellet fully dissolves. Pellets can also work their way out of the skin, called extrusion, and the insertion site can bleed, bruise, or become infected. Compounded hormone pellets are sometimes described as natural or safer than other hormone therapies. They are not risk free, and they carry the same types of hormone-related risks as other hormone treatments. National medical organizations, including the National Academies of Sciences, Engineering, and Medicine and the American College of Obstetricians and Gynecologists, recommend FDA-approved hormone therapies as the starting point for most patients. Compounded pellets are generally reserved for situations where your prescriber determines those products are not right for you. Bring your full health history to that conversation, including any history of blood clots, heart disease, or hormone-sensitive cancers.
Available Dosage Forms
Testosterone pellets
Compounded testosterone in a slow-release pellet, placed under the skin by a trained clinician in their office.
Estradiol pellets
Compounded estradiol in a slow-release pellet, placed under the skin by a trained clinician in their office.
Prescribers may consider this for
- Symptoms your prescriber associates with low testosterone, when commercially available products are not a fit
- Menopause-related symptoms, when your prescriber determines a manufactured option is not right for you
- Patients who have had trouble staying consistent with daily creams, patches, or injections
Common Questions
Visit or Call
7801 Mesquite Bend Dr. #108, Irving, TX 75063Pharmacy hours
Mon–Fri: 9:30 a.m.–3:30 p.m.
Sat–Sun: Closed
Related Services
Important Information
Compounded medications are prepared by a licensed pharmacist for an individual patient pursuant to a valid prescription from a licensed prescriber. Compounded medications are not FDA-approved. The FDA does not review compounded medications for safety, effectiveness, or quality before they are dispensed.
Prescription required. Compounded medications are dispensed only with a valid, patient-specific prescription. Ask your physician or prescriber whether a compounded medication is appropriate for you.
Information on this page is for educational purposes and is not medical advice. Individual results vary, and no outcome is guaranteed. Always consult your healthcare provider about your treatment options.
Questions? We're here to help.
Speak with a real person at America First Pharmacies in Irving, TX.